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| Diagnostic | Medulloblastoma | Statut d'étude | Closed |
| Phase | II |
| Age | 3 Years to 21 Years | Randomisation | NO |
| Ligne de traitement | First line treatment |
| Routes of Treatment Administration | Chemotherapy: Cisplatin (Given IV), Cyclophosphamide (Given IV), Lomustine (Given PO), Vincristine Sulfate (Given IV or via minibag)
Radiation: Radiation Therapy |
| Last Posted Update | 2025-02-20 |
| ClinicalTrials.gov # | NCT02724579 |
International Sponsor
Children's Oncology GroupPrincipal Investigators for Canadian Sites
Alberta Children's Hospital - Dr. Victor Lewis
BC Children's Hospital - Dr. David Dix
CancerCare Manitoba - Dr. Ashley Chopek
Janeway Child Health Centre - Dr. Lisa Goodyear
IWK Health Centre - Dr. Craig Erker
McMaster Children's Hospital at Hamilton Health Sciences - Dr. Uma Athale
Western Children's Hospital - Dr. Shayna Zelcer
Children's Hospital of Eastern Ontario - Dr. Donna Johnston
Hospital for Sick Children - Dr. Vijay Ramaswamy
Montreal Children's Hospital - Dr. Sharon Abish
Saskatoon Cancer Centre - Dr. Kathleen Felton Centres
Medical contact
Dr. Victor Lewis
Social worker/patient navigator contact
Wendy Pelletier
Clinical research contact
Debra Rich
Medical contact
Rebecca Deyell
Social worker/patient navigator contact
Ilana Katz
Clinical research contact
Hem/Onc/BMT Clinical Trials Unit
Medical contact
Dr. Magimairajan Vanan
Social worker/patient navigator contact
Rhéanne Bisson
Clinical research contact
Rebekah Hiebert
Megan Ridler
Kathy Hjalmarsson
Medical contact
Dr. Paul Moorehead
Social worker/patient navigator contact
Stephanie Eason
Clinical research contact
Bev Mitchell
Medical contact
Dr. Craig Erker
Dr. Conrad Fernandez
Dr. Ketan Kulkarni
Social worker/patient navigator contact
Rhonda Brophy
Clinical research contact
Tina Bocking
Medical contact
Dr. Carol Portwine
Social worker/patient navigator contact
Jane Cassano
Clinical research contact
Sabrina Millson
Medical contact
Dr. Alexandra Zorzi
Dr. Shayna Zelcer
Social worker/patient navigator contact
Cindy Milne Wren
Jessica Mackenzie Harris
Clinical research contact
Mariam Mikhail
Medical contact
Dr. Donna Johnston
Dr. Lesleigh Abbott
Dr. Nirav Thacker
Social worker/patient navigator contact
Sherley Telisma
Clinical research contact
Isabelle Laforest
Medical contact
Clinical Research Unit
Social worker/patient navigator contact
Clinical Research Unit
Clinical research contact
Stephanie Badour
Medical contact
Dr. Chris Mpofu
Social worker/patient navigator contact
Jillian Galambos
La Rae Beebe
Clinical research contact
Susan Kaban
Study Description
Cette étude de phase 2 examine l’efficacité de doses réduites de radiothérapie du cerveau et de la moelle épinière (craniospinale) en combinaison avec de la chimiothérapie, dans le traitement de patients atteints d’un type de tumeur cérébrale nouvellement diagnostiqué, le médulloblastome de sous-type WNT.
(par le biais du site Web : https://childrensoncologygroup.org/acns1422)
Inclusion Criteria
- Les patients sont âgés de 3 à 21 ans
- Le patient a été diagnostiqué récemment d’un médulloblastome à risque moyen de sous-type WNT
- Plusieurs autres critères d’inclusion et d’exclusion peuvent s’appliquer et seront examinés par votre équipe traitante.
D’autres critères d’inclusion et d’exclusion peuvent s’appliquer.
